Catecholamines and development of cardiac pacemaking: An intrinsically intimate relationship
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Catecholamines and development of cardiac pacemaking: an intrinsically intimate relationship.
A generation ago, a melding of imagination and experimental evidence led to the hypothesis that catecholamines were essential in establishing basal cardiac pacemaking rhythm. Subsequent discoveries of depolarizing "pacemaker" currents and viable adult catecholamine-deficient animals raised serious doubts about the necessity of catecholamines in pacemaking. However, the findings that catecholami...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2006
ISSN: 0008-6363
DOI: 10.1016/j.cardiores.2006.08.013